diff --git a/lib/reducers/message-reducer.js b/lib/reducers/message-reducer.js
--- a/lib/reducers/message-reducer.js
+++ b/lib/reducers/message-reducer.js
@@ -1371,7 +1371,15 @@
       messageStore: newMessageStore,
     };
   } else if (action.type === updateMultimediaMessageMediaActionType) {
-    const { messageID: id, currentMediaID, mediaUpdate } = action.payload;
+    const {
+      messageID: id,
+      currentMediaID,
+      mediaUpdate: _mediaUpdate,
+    } = action.payload;
+    // TODO: Remove this any-cast after RN 0.72 / Flow 0.202 update
+    // This is a workaround because `Shape<Media>` contains nested union types
+    // which current version of Flow cannot handle properly
+    const mediaUpdate = (_mediaUpdate: any);
     const message = messageStore.messages[id];
     invariant(message, `message with ID ${id} could not be found`);
     invariant(
@@ -1451,16 +1459,22 @@
         ) {
           // extract fields that are absent in encrypted_photo type
           const { uri, localMediaSelection, ...original } = singleMedia;
-          const { holder, encryptionKey, ...update } = mediaUpdate;
+          const {
+            holder: newHolder,
+            blobURI: newBlobURI,
+            encryptionKey,
+            ...update
+          } = mediaUpdate;
+          const blobURI = newBlobURI ?? newHolder;
           invariant(
-            holder && encryptionKey,
+            blobURI && encryptionKey,
             'holder and encryptionKey are required for encrypted_photo message',
           );
           media.push({
             ...original,
             ...update,
             type: 'encrypted_photo',
-            holder,
+            blobURI,
             encryptionKey,
           });
           replaced = true;
@@ -1471,18 +1485,22 @@
           const { uri, thumbnailURI, localMediaSelection, ...original } =
             singleMedia;
           const {
-            holder,
+            holder: newHolder,
+            blobURI: newBlobURI,
             encryptionKey,
-            thumbnailHolder,
+            thumbnailHolder: newThumbnailHolder,
+            thumbnailBlobURI: newThumbnailBlobURI,
             thumbnailEncryptionKey,
             ...update
           } = mediaUpdate;
+          const blobURI = newBlobURI ?? newHolder;
           invariant(
-            holder && encryptionKey,
+            blobURI && encryptionKey,
             'holder and encryptionKey are required for encrypted_video message',
           );
+          const thumbnailBlobURI = newThumbnailBlobURI ?? newThumbnailHolder;
           invariant(
-            thumbnailHolder && thumbnailEncryptionKey,
+            thumbnailBlobURI && thumbnailEncryptionKey,
             'thumbnailHolder and thumbnailEncryptionKey are required for ' +
               'encrypted_video message',
           );
@@ -1490,9 +1508,9 @@
             ...original,
             ...update,
             type: 'encrypted_video',
-            holder,
+            blobURI,
             encryptionKey,
-            thumbnailHolder,
+            thumbnailBlobURI,
             thumbnailEncryptionKey,
           });
           replaced = true;
@@ -1504,9 +1522,19 @@
           } else if (singleMedia.type === 'video') {
             media.push({ ...singleMedia, id: newID });
           } else if (singleMedia.type === 'encrypted_photo') {
-            media.push({ ...singleMedia, id: newID });
+            // TODO: Try removing this branching after Flow 0.202 update
+            if (singleMedia.blobURI) {
+              media.push({ ...singleMedia, id: newID });
+            } else if (singleMedia.holder) {
+              media.push({ ...singleMedia, id: newID });
+            }
           } else if (singleMedia.type === 'encrypted_video') {
-            media.push({ ...singleMedia, id: newID });
+            // TODO: Try removing this branching after Flow 0.202 update
+            if (singleMedia.blobURI) {
+              media.push({ ...singleMedia, id: newID });
+            } else if (singleMedia.holder) {
+              media.push({ ...singleMedia, id: newID });
+            }
           }
           replaced = true;
         }
diff --git a/lib/reducers/message-reducer.test.js b/lib/reducers/message-reducer.test.js
--- a/lib/reducers/message-reducer.test.js
+++ b/lib/reducers/message-reducer.test.js
@@ -66,6 +66,8 @@
   };
   const { messageStore: updatedMessageStore } = reduceMessageStore(
     messageStoreBeforeMediaUpdate,
+    // TODO: This should work after RN 0.72 / Flow 0.202 update
+    // $FlowFixMe
     updateMultiMediaMessageMediaAction,
     {},
   );
@@ -121,6 +123,8 @@
     const { messageStore: storeWithoutLocalMediaSelectionUpdate } =
       reduceMessageStore(
         messageStoreBeforeMediaUpdate,
+        // TODO: This should work after RN 0.72 / Flow 0.202 update
+        // $FlowFixMe
         actionWithoutLocalMediaSelectionUpdate,
         {},
       );
@@ -173,6 +177,8 @@
     const { messageStore: updatedMessageStoreWithReplacement } =
       reduceMessageStore(
         messageStoreBeforeMediaUpdate,
+        // TODO: This should work after RN 0.72 / Flow 0.202 update
+        // $FlowFixMe
         updateMultiMediaMessageMediaActionWithReplacement,
         {},
       );
diff --git a/native/input/input-state-container.react.js b/native/input/input-state-container.react.js
--- a/native/input/input-state-container.react.js
+++ b/native/input/input-state-container.react.js
@@ -974,7 +974,7 @@
         processedMedia.mediaType === 'encrypted_video'
           ? {
               type: processedMedia.mediaType,
-              holder: uri,
+              blobURI: uri,
               encryptionKey,
             }
           : {
@@ -1008,7 +1008,7 @@
             mediaUpdate: {
               ...updateMediaPayload.mediaUpdate,
               thumbnailID,
-              thumbnailHolder: thumbnailURI,
+              thumbnailBlobURI: thumbnailURI,
               thumbnailEncryptionKey,
               thumbnailThumbHash,
             },
diff --git a/web/input/input-state-container.react.js b/web/input/input-state-container.react.js
--- a/web/input/input-state-container.react.js
+++ b/web/input/input-state-container.react.js
@@ -348,7 +348,7 @@
           );
           return {
             id: serverID ? serverID : localID,
-            holder: uri,
+            blobURI: uri,
             type: 'encrypted_photo',
             encryptionKey,
             dimensions: shimmedDimensions,
@@ -1016,7 +1016,7 @@
         mediaUpdate = {
           ...mediaUpdate,
           type: outputMediaType,
-          holder: uri,
+          blobURI: uri,
           encryptionKey,
         };
       }